Article
TFAP2B influences the effect of dietary fat on weight loss under energy restriction.
PloS one - 1 Jan 2012
Stocks Tanja, Angquist Lars, Banasik Karina, Harder Marie N, Taylor Moira A, Hager Jörg, Arner Peter, Oppert Jean-Michel, Martinez J Alfredo, Polak Jan, Rousseau Francis, Langin Dominique, Rössner Stephan, Holst Claus, MacDonald Ian A, Kamatani Yoichiro, Pfeiffer Andreas F H, Kunesova Marie, Saris Wim H M, Hansen Torben, Pedersen Oluf, Astrup Arne, Sørensen Thorkild I A
Abstract excerpt
BACKGROUND: Numerous gene loci are related to single measures of body weight and shape. We investigated if 55 SNPs previously associated with BMI or waist measures, modify the effects of fat intake on weight loss and waist reduction under energy restriction. METHODS AND FINDINGS: Randomized controlled trial of 771 obese adults. ( REGISTRATION: ISRCTN25867281.) One SNP was selected for replication in another...
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