Article
FTO genotype, dietary protein, and change in appetite: the Preventing Overweight Using Novel Dietary Strategies trial.
The American journal of clinical nutrition - 1 May 2014
Huang Tao, Qi Qibin, Li Yanping, Hu Frank B, Bray George A, Sacks Frank M, Williamson Donald A, Qi Lu
Abstract excerpt
BACKGROUND: A common obesity-risk variant rs9939609 in the fat mass- and obesity-associated (FTO) gene was recently shown to affect appetite, and the gene is sensitive to the regulation of amino acids. OBJECTIVE: We examined the interaction between FTO genotype and protein intake on the long-term changes in appetite in a randomized controlled trial. DESIGN: We genotyped FTO rs9939609 in 737 overweight adults in...
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