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Article

Dietary Fat Modifies the Effects of FTO Genotype on Changes in Insulin Sensitivity.

The Journal of nutrition - 1 May 2015

Zheng Yan, Huang Tao, Zhang Xiaomin, Rood Jennifer, Bray George A, Sacks Frank M, Qi Lu

Abstract excerpt

BACKGROUND: The common variants in the fat mass and obesity-associated (FTO) gene have been associated with obesity and insulin resistance. Recently, studies also linked FTO variants with macronutrient intakes. OBJECTIVE: We aimed to investigate whether diet interventions varying in macronutrient...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Diet, Fat-Restricted
Share to Diet, High-Fat

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25761503
DOI: 10.3945/jn.115.210005
PMCID: PMC4408741

Genes

FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25761503-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Dietary Fat Modifies the Effects of FTO Genotype on Changes in Insulin Sensitivity.PMID 25761503Read ↗

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Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity.Semantic proximity Read ↗

Macronutrient intake as a mediator with FTO to increase body mass index.Semantic proximity Read ↗

FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.Semantic proximity Read ↗

Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans.Semantic proximity Read ↗

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Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents.Semantic proximity Read ↗

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