APOA5 genotype modulates 2-y changes in lipid profile in response to weight-loss diet intervention: the Pounds Lost Trial.

doi:10.3945/ajcn.112.040907

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Article

APOA5 genotype modulates 2-y changes in lipid profile in response to weight-loss diet intervention: the Pounds Lost Trial.

The American journal of clinical nutrition - 1 Oct 2012

Zhang Xiaomin, Qi Qibin, Bray George A, Hu Frank B, Sacks Frank M, Qi Lu

Abstract excerpt

BACKGROUND: The apolipoprotein A5 gene (APOA5) is a major gene that regulates lipid metabolism and is modulated by dietary factors. A novel variant rs964184 in APOA5 was identified to be associated with lipids in genome-wide association studies. OBJECTIVE: We examined whether this variant modified changes in lipid concentrations in response to a 2-y weight-loss diet intervention in a randomized trial. DESIGN: The...

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PMID: 22914552
DOI: 10.3945/ajcn.112.040907
PMCID: PMC3441115

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APOA5

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