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Article

UVRAG

10 Aug 2012

Abstract excerpt

UVRAG is a promoter of the autophagy pathway, and its deficiency may fuel the development of cancers. Intriguingly, our recent study has demonstrated that this protein also mediates the repair of damaged DNA and patrols centrosome stability, mechanisms that commonly prevent cancer progression, in a manner independent of its role in autophagy signaling. Given the central role of UVRAG in genomic stability and...

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Identifiers

PMID: 22885520
DOI: 10.4161/auto.21035

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