Article
Autophagy modulator plays a part in UV protection.
Autophagy - 1 Sept 2016
Yang Yongfei, Quach Christine, Liang Chengyu
Abstract excerpt
Ultraviolet (UV)-induced DNA damage is a major risk factor for skin cancers including melanoma. UVRAG, originally identified to complement UV sensitivity in xeroderma pigmentosum (XP), has since been implicated in modulating macroautophagy/autophagy, in coordinating different intracellular trafficking pathways, and in maintaining chromosomal stability. Intriguingly, our recent study has demonstrated that UVRAG...
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