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Article

Uvragtargeting byMir125aandMir351modulates autophagy associated withEwsr1deficiency

4 May 2015

Abstract excerpt

The EWSR1 (EWS RNA-binding protein 1/Ewing Sarcoma Break Point Region 1) gene encodes a RNA/DNA binding protein that is ubiquitously expressed and involved in various cellular processes. EWSR1 deficiency leads to impairment of development and accelerated senescence but the mechanism is not known. Herein, we found that EWSR1 modulates the Uvrag (UV radiation resistance associated) gene at the post-transcription...

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PMID: 25946189
DOI: 10.1080/15548627.2015.1035503

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