Article
Fragment c gamma receptor gene polymorphisms and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians.
Breast cancer research and treatment - 1 Apr 2011
Iwasaki Motoki, Shimada Naoki, Kasuga Yoshio, Yokoyama Shiro, Onuma Hiroshi, Nishimura Hideki, Kusama Ritsu, Hamada Gerson S, Nishimoto Ines N, Iyeyasu Hirofumi, Motola Juvenal, Laginha Fábio M, Anzai Roberto, Tsugane Shoichiro
Abstract excerpt
Previous studies showing the presence of antibodies against tumor-associated antigens in healthy individuals suggest that antibody-dependent cell cytotoxicity (ADCC) might play a role in the development of breast cancer. We hypothesized that functional polymorphisms in fragment c gamma receptor (FcgR) genes were associated with breast cancer risk. We conducted hospital-based case-control studies of patients aged...
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