Article
Early antidepressant efficacy modulation by glutamatergic gene variants in the STAR*D.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jul 2013
Fabbri Chiara, Drago Antonio, Serretti Alessandro
Abstract excerpt
The glutamatergic system has been suggested as a modulator of rapid antidepressant response. Thus, 44 glutamatergic genes were selected according to the literature and investigated in 1541 major depressive patients from the STAR*D genome wide dataset. Outcomes of interest were early response (2nd week) and late response (from the 4th to the 14th week) compared to non-response and stability of response through the...
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