Article
[Association between amino acid mutations in Gag protein and human leukocyte antigen class I alleles in human immunodeficiency virus-1 B' infected Han Chinese people].
Zhonghua yi xue za zhi - 8 May 2012
Han Xiao-xu, Zhang Hui, Zhao Bin, Chen Ou, Zhang Cheng, Ji Yang-tao, Zhang Zi-ning, Cui Wei-guo, Liu Bao-gui, Duan Song, Shang Hong
Abstract excerpt
OBJECTIVE: To explore the human leukocyte antigen (HLA)-associated mutations in Gag protein of B' clade (human immunodeficiency virus-1) HIV-1 infected Han Chinese people and evaluate the impact of HLA associated Gag mutations on the disease progression of HIV infection. METHODS: A total of 95 B' clade HIV-1 infected Han Chinese cases were recruited. The gag sequences were amplified from viral RNA and sequenced...
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