The small regulatory RNA FasX controls pilus expression and adherence in the human bacterial pathogen group A Streptococcus

Abstract excerpt

Bacterial pathogens use cell surface-associated adhesion molecules to promote host attachment and colonization, and the ability to modulate adhesion expression is critical to pathogen success. Here, we show that the human-specific pathogen the group A Streptococcus (GAS) uses a small regulatory RNA (sRNA) to regulate the expression of adhesive pili. The...

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