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A small regulatory RNA alters Staphylococcus aureus virulence by titrating RNAIII activity

8 Sept 2021

Abstract excerpt

Staphylococcus aureus is an opportunistic human and animal pathogen with an arsenal of virulence factors that are tightly regulated during bacterial infection. The latter is achieved through a sophisticated network of regulatory proteins and regulatory RNAs. Here, we describe the involvement of a novel prophage-carried small regulatory S. aureus RNA, SprY, in the control of virulence genes. An MS2-affinity...

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PMID: 34554192
DOI: 10.1093/nar/gkab782

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