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The Regulatory Small RNA MarS Supports Virulence of Streptococcus pyogenes

19 Sept 2017

Abstract excerpt

Small regulatory RNAs (sRNAs) play a role in the control of bacterial virulence gene expression. In this study, we investigated an sRNA that was identified in Streptococcus pyogenes (group A Streptococcus, GAS) but is conserved throughout various streptococci. In a deletion strain, expression of mga, the gene encoding the multiple virulence gene regulator, was reduced. Accordingly, transcript and proteome...

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PMID: 28947755
DOI: 10.1038/s41598-017-12507-z

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