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Article

Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains.

Scientific reports - 26 Sept 2017

Hsu Kai-Cheng, Hung Hui-Chen, HuangFu Wei-Chun, Sung Tzu-Ying, Eight Lin Tony, Fang Ming-Yu, Chen I-Jung, Pathak Nikhil, Hsu John T-A, Yang Jinn-Moon

Abstract excerpt

Influenza is an annual seasonal epidemic that has continually drawn public attentions, due to the potential death toll and drug resistance. Neuraminidase, which is essential for the spread of influenza virus, has been regarded as a valid target for the treatment of influenza infection. Although neuraminidase drugs have been developed, they are susceptible to drug-resistant mutations in the sialic-binding site. In...

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Source

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Identifiers

PMID: 28951584
DOI: 10.1038/s41598-017-12101-3
PMCID: PMC5615050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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