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Article

Peramivir binding affinity with influenza A neuraminidase and research on its mutations using an induced-fit docking approach.

SAR and QSAR in environmental research - 1 Dec 2019

Tran-Nguyen V K, Le M T, Tran T D, Truong V D, Thai K M

Abstract excerpt

Influenza A virus (IAV) has caused epidemic infections worldwide, with many strains resistant to inhibitors of a surface protein, neuraminidase (NA), due to point mutations on its structure. A novel NA inhibitor named peramivir was recently approved, but no exhaustive computational research regarding its binding affinity with wild-type and mutant NA has been conducted. In this study, a thorough investigation of...

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Identifiers

PMID: 31645133
DOI: 10.1080/1062936X.2019.1679248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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