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Article

MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression.

PloS one - 1 Jan 2012

Kong Xiangjun, Li Gaopeng, Yuan Yan, He Yan, Wu Xiaoli, Zhang Weijie, Wu Zhengsheng, Chen Tingting, Wu Wenyong, Lobie Peter E, Zhu Tao

Abstract excerpt

Focal adhesion kinase (FAK) is an important mediator of extracellular matrix integrin signaling, cell motility, cell proliferation and cell survival. Increased FAK expression is observed in a variety of solid human tumors and increased FAK expression and activity frequently correlate with metasta...

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Identifiers

PMID: 22876288
DOI: 10.1371/journal.pone.0041523
PMCID: PMC3410899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22876288-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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