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Article

BMP7 influences proliferation, migration, and invasion of breast cancer cells.

Cancer letters - 8 Mar 2009

Alarmo Emma-Leena, Pärssinen Jenita, Ketolainen Johanna M, Savinainen Kimmo, Karhu Ritva, Kallioniemi Anne

Abstract excerpt

Bone morphogenetic protein 7 (BMP7) is a signaling molecule originally identified based on its ability to form bone. It is essential during development, and more recently has also been implicated in cancer pathogenesis. We have recently shown that BMP7 is overexpressed in breast cancer, and that this increased expression is associated with early bone metastasis formation. In the present study, we explored the...

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Source

Identifiers

PMID: 18980801
DOI: 10.1016/j.canlet.2008.09.028

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BMP7

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