Article
Association of OX40L polymorphisms with sporadic breast cancer in northeast Chinese Han population.
PloS one - 1 Jan 2012
Weiguang Yuan, Dalin Li, Lidan Xu, Yonggang Cai, Shuang Chen, Yanhong Liu, Fengyan Xu, Zhenkun Fu, Da Pang, Dianjun Li
Abstract excerpt
OX40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of OX40-OX40L is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. The genetic variants of OX40L can increase the risk of SLE, atherosclerosis, systemic sclerosis and show...
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