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Article

OX40, OX40L and Autoimmunity: a Comprehensive Review.

Clinical reviews in allergy & immunology - 1 Jun 2016

Webb Gwilym J, Hirschfield Gideon M, Lane Peter J L

Abstract excerpt

The tumour necrosis factor receptor OX40 (CD134) is activated by its cognate ligand OX40L (CD134L, CD252) and functions as a T cell co-stimulatory molecule. OX40-OX40L interactions have been proposed as a potential therapeutic target for treating autoimmunity. OX40 is expressed on activated T cells, and in the mouse at rest on regulatory T cells (Treg). OX40L is found on antigen-presenting cells, activated T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26215166
DOI: 10.1007/s12016-015-8498-3

Genes

TNFRSF4
TNFSF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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