Lysyl oxidase 473 G>A polymorphism and breast cancer susceptibility in Chinese Han population.

doi:10.1089/dna.2010.1098

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Article

Lysyl oxidase 473 G>A polymorphism and breast cancer susceptibility in Chinese Han population.

DNA and cell biology - 1 Feb 2011

Ren Jinghua, Wu Xiaoling, He Wenshan, Shao Jun, Cheng Bo, Huang Tao

Abstract excerpt

Lysyl oxidase (LOX) is an extracellular enzyme critical for the cross-linking of collagens and elastin. The LOX gene has also been shown to inhibit the transforming activity of Ras oncogene signaling. Recently, a single-nucleotide polymorphism (SNP) of LOX G473A (rs1800449) has been demonstrated to be associated with increased risk of breast cancer in African American women. In this hospital-based case-control...

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PMID: 20929399
DOI: 10.1089/dna.2010.1098

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rs1800449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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