Article
LFA-1 gene polymorphisms are associated with the sporadic infiltrative duct breast carcinoma in Chinese Han women of Heilongjiang Province.
Breast cancer research and treatment - 1 May 2011
Fu Zhenkun, Jiao Mingli, Zhang Mingyan, Xu Fengyan, Yuan Weiguang, Pang Da, Li Dianjun
Abstract excerpt
The infiltrative duct carcinoma (IDC) is the most common malignant breast cancer in females and genetic factors appear to play a significant role in the susceptibility of IDC. The LFA-1 is a crucial co-stimulatory molecule in immune system and may affect the development of breast IDC. In order to clarify the association of LFA-1 polymorphisms with IDC, a case-control study was conducted in women from Heilongjiang...
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