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Article

No evidence for breast cancer susceptibility associated with variants of BRD7, a component of p53 and BRCA1 pathways.

Familial cancer - 1 Dec 2012

Penkert Judith, Schlegelberger Brigitte, Steinemann Doris, Gadzicki Dorothea

Abstract excerpt

BRD7 (bromodomain 7), a subunit of poly-bromo-associated BRG1-associated factor (PBAF)-specific Swi/Snf chromatin remodeling complexes, has been proposed as a tumour suppressor protein following its identification as an important component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. As low BRD7 expression levels have been linked to p53-wild-type breast tumour cells, we hypothesized...

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Source

Identifiers

PMID: 22864638
DOI: 10.1007/s10689-012-9556-0

Genes

BRD7
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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No evidence for breast cancer susceptibility associated with variants of BRD7, a component of p53 and BRCA1 pathways.PMID 22864638Read ↗

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