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Article

Analysis of the Birt-Hogg-Dubé (BHD) tumour suppressor gene in sporadic renal cell carcinoma and colorectal cancer.

Journal of medical genetics - 1 Nov 2003

da Silva N Fernandes, Gentle D, Hesson L B, Morton D G, Latif F, Maher E R

Abstract excerpt

Germline mutations in the BHD gene cause the dominantly inherited cancer susceptibility disorder, Birt-Hogg-Dubé (BHD) syndrome. Individuals with BHD are reported to have an increased risk of renal cell carcinoma (RCC) and of colorectal polyps and cancer. The BHD gene maps to 17p11.2, and to investigate whether somatic inactivation of the BHD gene region is implicated in the pathogenesis of sporadic RCC and...

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Identifiers

PMID: 14627671
DOI: 10.1136/jmg.40.11.820
PMCID: PMC1735328

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of the Birt-Hogg-Dubé (BHD) tumour suppressor gene in sporadic renal cell carcinoma and colorectal cancer.PMID 14627671Read ↗

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