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Article

Cancer predisposing BARD1 mutations in breast-ovarian cancer families.

Breast cancer research and treatment - 1 Jan 2012

Ratajska Magdalena, Antoszewska Ewelina, Piskorz Anna, Brozek Izabela, Borg Åke, Kusmierek Hanna, Biernat Wojciech, Limon Janusz

Abstract excerpt

The breast cancer susceptibility gene BARD1 (BRCA1-associated RING domain protein, MIM# 601593) acts with BRCA1 in DNA double-strand break (DSB) repair and also in apoptosis initiation. We screened 109 BRCA1/2 negative high-risk breast and/or ovarian cancer patients from North-Eastern Poland for BARD1 germline mutations using a combination of denaturing high-performance liquid chromatography and direct...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21344236
DOI: 10.1007/s10549-011-1403-8

Genes

BARD1
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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