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Article

BARD1 and breast cancer in Poland.

Breast cancer research and treatment - 1 Jan 2008

Jakubowska Anna, Cybulski Cezary, Szymańska Anna, Huzarski Tomasz, Byrski Tomasz, Gronwald Jacek, Debniak Tadeusz, Górski Bohdan, Kowalska Elzbieta, Narod Steven A, Lubiński Jan

Abstract excerpt

PURPOSE: To investigate whether or not a genetic variant in BARD1 (Cys557Ser) contributes to early-onset breast cancer in Poland, or modifies the risk of breast cancer in women with an inherited predisposition to breast cancer. EXPERIMENTAL DESIGN: We studied 3,188 unselected Polish women with breast cancer and 1,038 healthy controls. All women were genotyped for the BARD1 Cys557Ser variant and for known founder...

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BRCA1 Protein
Cell Cycle Proteins
Checkpoint Kinase 2
Poland
Risk

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Suppressor Proteins

Ubiquitin-Protein Ligases

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Identifiers

PMID: 17333333
DOI: 10.1007/s10549-007-9537-4

Genes

BARD1
BRCA1
CHEK2

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BARD1 and breast cancer in Poland.PMID 17333333Read ↗

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Cancer predisposing BARD1 mutations in breast-ovarian cancer families.Semantic proximity Read ↗

Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies.Semantic proximity Read ↗

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