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Article

Lack of association between BARD1 Cys557Ser variant and breast cancer risk: a meta-analysis of 11,870 cases and 7,687 controls.

Journal of cancer research and clinical oncology - 1 Oct 2011

Ding Da-Peng, Zhang Ying, Ma Wen-Li, He Xiao-Feng, Wang Wei, Yu Hai-Lang, Guo Yu-Bo, Zheng Wen-Ling

Abstract excerpt

PURPOSE: The BRCA1-associated RING domain (BARD1) gene has been identified as a high-penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. Some association studies suggested that the BRAD1 Cys557Ser variant might be associated with increased risk of breast cancer, but the results remain conflicting...

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Source

Identifiers

PMID: 21809034
DOI: 10.1007/s00432-011-1006-0

Genes

BRCA1
BARD1

Provenance

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association between BARD1 Cys557Ser variant and breast cancer risk: a meta-analysis of 11,870 cases and 7,687 controls.PMID 21809034Read ↗

BARD1 variants Cys557Ser and Val507Met in breast cancer predisposition.Semantic proximity Read ↗

The BARD1 Cys557Ser variant and risk of familial breast cancer in a South-American population.Semantic proximity Read ↗

Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility: a case-control analysis.Semantic proximity Read ↗

Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers.Semantic proximity Read ↗

BARD1 and breast cancer in Poland.Semantic proximity Read ↗

Mutations in exon region of BRCA1-related RING domain 1 gene and risk of breast cancer.Semantic proximity Read ↗

Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies.Semantic proximity Read ↗

Literature Review of BARD1 as a Cancer Predisposing Gene with a Focus on Breast and Ovarian Cancers.Semantic proximity Read ↗

Mutation screening of the BARD1 gene: evidence for involvement of the Cys557Ser allele in hereditary susceptibility to breast cancer.Semantic proximity Read ↗

BARD1 mystery: tumor suppressors are cancer susceptibility genesSemantic proximity Read ↗

Identification of functional SNPs in BARD1 gene and in silico analysis of damaging SNPs: based on data procured from dbSNP database.Semantic proximity Read ↗

Cancer predisposing BARD1 mutations in breast-ovarian cancer families.Semantic proximity Read ↗

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