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Article

Role of rare germline copy number variation in melanoma-prone patients.

Future oncology (London, England) - 1 Jun 2016

Fidalgo Felipe, Rodrigues Tatiane Cristina, Silva Amanda Gonçalves, Facure Luciana, de Sá Bianca Costa Soares, Duprat João Pedreira, Achatz Maria Isabel, Rosenberg Carla, Carraro Dirce Maria, Krepischi Ana Cristina Victorino

Abstract excerpt

AIM: This work evaluates a possible causative role for germline copy number variants (CNVs) in melanoma predisposition. PATIENTS & METHODS: A total of 41 melanoma-prone Brazilian patients were investigated for CNVs using 850K single nucleotide polymorphism arrays. RESULTS: Ten rare CNVs were identified in nine patients, comprising 54 known genes, mostly related to cancer. In silico analyses revealed gene...

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Share to Germ-Line Mutation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to IDH1 gene

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 27020340
DOI: 10.2217/fon.16.22

Genes

ANGPT1
GCNT2
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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