Article

The rate of de novo CNVs in healthy controls

2019-11-29

Abstract excerpt

<h4>Background</h4> Copy number variation (CNV) is an important cause for human disease. Due to relatively high selection pressure operating against pathogenic CNVs, their rate is maintained in the population by de novo formation. The rates of de novo CNVs are increased in neurodevelopmental disorders. However only a few studies have been performed on relatively healthy individuals, making it problematic to cal...

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Literature Corpus work: 90063400-af3c-54bb-883f-dda3a97acb69
DOI: 10.1101/857797

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