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Article

An environmental epigenetic study of ADRB 2 5′‐ UTR methylation and childhood asthma severity

18 Jun 2012

Abstract excerpt

BACKGROUND: Beta-2 adrenergic receptor (ADRB2) is the primary target of both short- and long-acting beta-agonist asthma medications. ADRB2 5'-UTR methylation changes in blood have the potential to act as a surrogate biomarker of responsiveness to beta-agonist treatment and childhood asthma severity. OBJECTIVE: To study the association between ADRB2 5'-UTR methylation, NO (2) exposure and childhood asthma...

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Identifiers

PMID: 22862293
DOI: 10.1111/j.1365-2222.2012.04055.x

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