Influence of ADRB2 variants on bronchodilator response and asthma control in a mixed population.

doi:10.36416/1806-3756/e20250066

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Article

Influence of ADRB2 variants on bronchodilator response and asthma control in a mixed population.

Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia - 1 Jan 2025

Rodrigues Pedro Augusto Silva Dos Santos, Cruz Filho Álvaro Augusto Souza da, Teixeira Helena Mariana Pitangueira, Gomes Luciano Gama da Silva, Silva Hatilla Dos Santos, Rodrigues Juliana Lopes, Oliveira Almirane Lima de, Santana Cinthia Vila Nova, Chagas Gabriela Pimentel Pinheiro das, Figueiredo Camila Alexandrina Viana de, Costa Ryan Dos Santos

Abstract excerpt

OBJECTIVE: Given that b2 agonists constitute the primary treatment for asthma and that treatment response varies as a result of polymorphisms in the ADRB2 gene, we sought to investigate the associations between ADRB2 gene variants and bronchodilator response (BDR) in asthma patients. METHODS: A genetic database comprising 813 individuals was analyzed for variants in the ADRB2 gene. A longitudinal analysis of...

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Topics

Humans
Asthma
Receptors, Adrenergic, beta-2
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Bronchodilator Agents

Middle Aged

Adult

Longitudinal Studies

Aged

Genotype

Polymorphism, Single Nucleotide

Alleles

Severity of Illness Index

Young Adult

Age Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 40834135
DOI: 10.36416/1806-3756/e20250066
PMCID: PMC12401121

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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