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Article

Methylomic markers of persistent childhood asthma: a longitudinal study of asthma-discordant monozygotic twins

1 Dec 2015

Abstract excerpt

BACKGROUND: Asthma is the most common chronic inflammatory disorder in children. The aetiology of asthma pathology is complex and highly heterogeneous, involving the interplay between genetic and environmental risk factors that is hypothesized to involve epigenetic processes. Our aim was to explore whether methylomic variation in early childhood is associated with discordance for asthma symptoms within...

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PMID: 26691723
DOI: 10.1186/s13148-015-0163-4

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