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Article

Mapping genetic variants associated with beta-adrenergic responses in inbred mice.

PloS one - 1 Jan 2012

Hersch Micha, Peter Bastian, Kang Hyun Min, Schüpfer Fanny, Abriel Hugues, Pedrazzini Thierry, Eskin Eleazar, Beckmann Jacques S, Bergmann Sven, Maurer Fabienne

Abstract excerpt

β-blockers and β-agonists are primarily used to treat cardiovascular diseases. Inter-individual variability in response to both drug classes is well recognized, yet the identity and relative contribution of the genetic players involved are poorly understood. This work is the first genome-wide association study (GWAS) addressing the values and susceptibility of cardiovascular-related traits to a selective...

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Share to Adrenergic beta-Agonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22859963
DOI: 10.1371/journal.pone.0041032
PMCID: PMC3409184

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