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Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis

1 Jun 2012

Abstract excerpt

Chondrogenesis occurs as a result of mesenchymal cell condensation and chondroprogenitor cell differentiation. Following chondrogenesis, the chondrocytes remain as resting cells to form the articular cartilage or undergo proliferation, terminal differentiation to chondrocyte hypertrophy, and apoptosis in a process termed endochondral ossification, whereby the hypertrophic cartilage is replaced by bone. Human...

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PMID: 22859926
DOI: 10.1177/1759720x12448454

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