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Chemical genetics: budding yeast as a platform for drug discovery and mapping of genetic pathways.

Molecules (Basel, Switzerland) - 2 Aug 2012

Enserink Jorrit M

Abstract excerpt

The budding yeast Saccharomyces cerevisiae is a widely used model organism, and yeast genetic methods are powerful tools for discovery of novel functions of genes. Recent advancements in chemical-genetics and chemical-genomics have opened new avenues for development of clinically relevant drug treatments. Systematic mapping of genetic networks by high-throughput chemical-genetic screens have given extensive...

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PMID: 22858845
DOI: 10.3390/molecules17089258
PMCID: PMC6268143

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