Article
Studying phospholipid metabolism using yeast systematic and chemical genetics.
Methods (San Diego, Calif.) - 1 Jun 2005
Fairn Gregory D, McMaster Christopher R
Abstract excerpt
Most phospholipid metabolic pathways in the budding yeast Saccharomyces cerevisiae are analogous to their mammalian counterparts. The biological tractability of yeast provides for an opportunity to rapidly determine functions of specific lipids or lipid metabolic pathways using both classical and chemical-genetic techniques. The recent generation of the yeast genome deletion collection revealed that approximately...
Topics
- Automation
- Culture Media
- Databases, Genetic
- Diploidy
- Fungal Proteins
- Gene Deletion
- Genetic Techniques
- Genome, Fungal
- Haploidy
- Internet
- Lipid Metabolism
- Models, Genetic
