Article
[Relation of genetic variants of CYP2A6 with tobacco dependence and smoking habit in Chilean subjects. A pilot study].
Revista medica de Chile - 1 Apr 2012
Cáceres Dante D, Alvarado Sergio A, Martínez Paulina, Quiñones Luis A
Abstract excerpt
BACKGROUND: Genetic and metabolic factors associated with nicotine metabolism may be related to smoking behavior. AIM: To assess the prevalence of allelic and genotype variants of CYP2A6 in a sample of Chilean subjects and to evaluate their relationship with smoking and tobacco dependence. MATERIAL AND METHODS: The genotype frequencies for *2, *3 and *4 of CYP2A6*1 (wild type) gene were determined by polymerase...
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