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Article

Genomic diversity of mec regulator genes in methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.

Epidemiology and infection - 1 Oct 1996

Kobayashi N, Taniguchi K, Kojima K, Urasawa S, Uehara N, Omizu Y, Kishi Y, Yagihashi A, Kurokawa I, Watanabe N

Abstract excerpt

Low-affinity penicillin-binding protein PBP-2a encoded by mecA is closely related to methicillin resistance in staphylococci, and expression of PBP-2a is controlled by regulator elements encoded by mecR1 and mecI which are located adjacent to mecA on the chromosome. Deletion or mutation which occurred in mec regulator gene is considered to be associated with constitutive production of PBP-2a. The distribution of...

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Identifiers

PMID: 8870626
DOI: 10.1017/s0950268800001461
PMCID: PMC2271699

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Source receipt: pubmed, retrieved 7 Sept 2026.

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