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Article

IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Sept 2012

Moorman Anthony V, Schwab Claire, Ensor Hannah M, Russell Lisa J, Morrison Heather, Jones Lisa, Masic Dino, Patel Bella, Rowe Jacob M, Tallman Martin, Goldstone Anthony H, Fielding Adele K, Harrison Christine J

Abstract excerpt

PURPOSE: To determine the prevalence and prognostic impact of significant acute lymphoblastic leukemia (ALL) -related genes: CRLF2 deregulation (CRLF2-d), IGH@ translocations (IGH@-t), and deletions of CDKN2A/B, IKZF1, PAX5, ETV6, RB1, BTG1, and EBF1 in adolescents and adults. PATIENTS AND METHODS: The cohort comprised 454 patients (age 15 to 60 years old) treated on the multicenter United Kingdom Acute...

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Source

Identifiers

PMID: 22851563
DOI: 10.1200/JCO.2011.40.3907

Genes

CRLF2
IGH
IKZF1
BTG1
EBF1
ETV6
PAX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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