Article
Evaluation of pharmacogenetic algorithm for warfarin dose requirements in Japanese patients.
Circulation journal : official journal of the Japanese Circulation Society - 1 May 2010
Takeuchi Fumihiko, Kashida Mitsuo, Okazaki Osamu, Tanaka Yuriko, Fukuda Shoji, Kashima Toshitaka, Hosaka Shigeru, Hiroe Michiaki, Kimura Sosuke, Kato Norihiro
Abstract excerpt
BACKGROUND: Warfarin dosing is difficult to establish because of considerable interindividual variation. Thus, warfarin pharmacogenetics have attracted particular interest in relation to appropriate control of anticoagulation. METHODS AND RESULTS: The 200 eligible subjects were chosen from partic...
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