Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2009

Agrawal Arpana, Wetherill Leah, Dick Danielle M, Xuei Xiaoling, Hinrichs Anthony, Hesselbrock Victor, Kramer John, Nurnberger John I, Schuckit Marc, Bierut Laura J, Edenberg Howard J, Foroud Tatiana

Abstract excerpt

Genomic studies of cannabis use disorders have been limited. The cannabinoid receptor 1 gene (CNR1) on chromosome 6q14-15 is an excellent candidate gene for cannabis dependence due to the important role of the G-protein coupled receptor encoded by this gene in the rewarding effects of Delta9-tetr...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Gene Frequency

Share to Linkage Disequilibrium

Share to Marijuana Abuse

Share to Receptor, Cannabinoid, CB1

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 19016476
DOI: 10.1002/ajmg.b.30881
PMCID: PMC2703788

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19016476-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.PMID 19016476Read ↗

The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults.Semantic proximity Read ↗

Cannabinoid receptor 1 gene association with nicotine dependence.Semantic proximity Read ↗

A genome-wide association study of DSM-IV cannabis dependence.Semantic proximity Read ↗

CNR1 gene polymorphisms in addictive disorders: a systematic review and a meta-analysis.Semantic proximity Read ↗

Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents.Semantic proximity Read ↗

Association study of a cannabinoid receptor gene (CNR1) polymorphism and schizophrenia.Semantic proximity Read ↗

Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks.Semantic proximity Read ↗

Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis.Semantic proximity Read ↗

Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse.Semantic proximity Read ↗

Genome-wide association study identifies a novel locus for cannabis dependence.Semantic proximity Read ↗

CNR1 variation modulates risk for drug and alcohol dependence.Semantic proximity Read ↗

Allele-specific differences in activity of a novel cannabinoid receptor 1 (CNR1) gene intronic enhancer in hypothalamus, dorsal root ganglia, and hippocampus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.