Article
Mannose-binding lectin gene polymorphism and risk factors for cardiovascular disease in postmenopausal women.
Molecular immunology - 1 Sept 2014
Orsatti Claudio Lera, Nahás Eliana Aguiar Petri, Nahas-Neto Jorge, Orsatti Fabio Lera, Linhares Iara Moreno, Witkin Steven Sol
Abstract excerpt
BACKGROUND: Inflammatory responses may be altered in postmenopausal women and predispose to cardiovascular disease (CVD). Genetic factors can also influence susceptibility to CVD. Mannose-binding lectin (MBL) is a component of the innate immune system and an activator of the complement cascade. We evaluated the association of genetic polymorphism of MBL (MBL2) on risk factors for CVD in postmenopausal women....
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