Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Requirement for a uroplakin 3a-like protein in the development of zebrafish pronephric tubule epithelial cell function, morphogenesis, and polarity.

PloS one - 1 Jan 2012

Mitra Shalini, Lukianov Stefan, Ruiz Wily G, Cianciolo Cosentino Chiara, Sanker Subramaniam, Traub Linton M, Hukriede Neil A, Apodaca Gerard

Abstract excerpt

Uroplakin (UP)3a is critical for urinary tract development and function; however, its role in these processes is unknown. We examined the function of the UP3a-like protein Upk3l, which was expressed at the apical surfaces of the epithelial cells that line the pronephric tubules (PTs) of the zebrafish pronephros. Embryos treated with upk3l-targeted morpholinos showed decreased pronephros function, which was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Polarity
Share to Epithelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Kidney Tubules

Share to Morphogenesis

Share to Urogenital Abnormalities

Share to Zebrafish

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22848617
DOI: 10.1371/journal.pone.0041816
PMCID: PMC3404999

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Requirement for a uroplakin 3a-like protein in the development of zebrafish pronephric tubule epithelial cell function, morphogenesis, and polarity.PMID 22848617Read ↗

Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout miceSemantic proximity Read ↗

Uroplakin 1b is critical in urinary tract development and urothelial differentiation and homeostasis.Semantic proximity Read ↗

Upk3b is dispensable for development and integrity of urothelium and mesothelium.Semantic proximity Read ↗

Uroplakins: new molecular players in the biology of urinary tract malformations.Semantic proximity Read ↗

Zebrafish: a model system for the study of vertebrate renal development, function, and pathophysiologySemantic proximity Read ↗

Par3A and Par3B orchestrate podocyte architecture by regulating RhoA levelsSemantic proximity Read ↗

An Essential Role of the Universal Polarity Protein, aPKCλ, on the Maintenance of Podocyte Slit DiaphragmsSemantic proximity Read ↗

Podocyte polarity signallingSemantic proximity Read ↗

pdzrn3 is required for pronephros morphogenesis in Xenopus laevis.Semantic proximity Read ↗

Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells.Semantic proximity Read ↗

Nephrocystin-3 is required for ciliary function in zebrafish embryos.Semantic proximity Read ↗

Nephrocystin-4 is required for pronephric duct-dependent cloaca formation in zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.