Article
Uroplakins: new molecular players in the biology of urinary tract malformations.
Kidney international - 1 Feb 2007
Jenkins D, Woolf A S
Abstract excerpt
The uroplakins (UPs) are a family of proteins which associate with each other and form plaques on the apical surface of the urothelium. These plaques contribute to a permeability barrier, preventing the influx of urine from the urinary tract lumen. Urinary tract malformations associated with human and mouse UP mutations, the human fetal expression patterns of UPs and experiments in Xenopus oocytes are...
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