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Article

Mapping MKP-3/FOXO1 interaction and evaluating the effect on gluconeogenesis.

PloS one - 1 Jan 2012

Jiao Ping, Feng Bin, Xu Haiyan

Abstract excerpt

BACKGROUND: MAP kinase phosphatase 3 (MKP-3) is known to attenuate the ERK signaling pathway. It has been recently demonstrated that MKP-3 is also a player in promoting hepatic glucose output in obese state by interacting and activating FOXO1. Reduction of hepatic MKP-3 expression is sufficient t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22848439
DOI: 10.1371/journal.pone.0041168
PMCID: PMC3405053

Genes

FOXO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22848439-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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