Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiscale modeling and analysis of planar cell polarity in the Drosophila wing.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Gao Qian, Gilbert David, Heiner Monika, Liu Fei, Maccagnola Daniele, Tree David

Abstract excerpt

Modeling across multiple scales is a current challenge in Systems Biology, especially when applied to multicellular organisms. In this paper, we present an approach to model at different spatial scales, using the new concept of Hierarchically Colored Petri Nets (HCPN). We apply HCPN to model a tissue comprising multiple cells hexagonally packed in a honeycomb formation in order to describe the phenomenon of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Polarity
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila

Share to Models, Biological

Share to Mutation

Share to Systems Biology

Share to Wings, Animal

Source

Identifiers

PMID: 22848136
DOI: 10.1109/TCBB.2012.101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiscale modeling and analysis of planar cell polarity in the Drosophila wing.PMID 22848136Read ↗

Disentangling a Complex Response in Cell Reprogramming and Probing the Waddington Landscape by Automatic Construction of Petri NetsSemantic proximity Read ↗

Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram.Semantic proximity Read ↗

Modeling polarity buildup and cell fate decision in the fly eye: insight into the connection between the PCP and Notch pathways.Semantic proximity Read ↗

Modelling the Molecular Interactions in the Flower Developmental Network of Arabidopsis thaliana.Semantic proximity Read ↗

Interlinked nonlinear subnetworks underlie the formation of robust cellular patterns in Arabidopsis epidermis: a dynamic spatial model.Semantic proximity Read ↗

Constructing quantitative models from qualitative mutant phenotypes: preferences in selecting sensory organ precursors.Semantic proximity Read ↗

Phenotypic and dynamical transitions in model genetic networks. II. Application to the evolution of segmentation mechanisms.Semantic proximity Read ↗

Controllability and observability of Boolean networks arising from biology.Semantic proximity Read ↗

Establishment and maintenance of planar epithelial cell polarity by asymmetric cadherin bridges: a computer model.Semantic proximity Read ↗

Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach.Semantic proximity Read ↗

Modular logical modelling of the budding yeast cell cycle.Semantic proximity Read ↗

Mathematical modeling of planar cell polarity to understand domineering nonautonomy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.