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Article

Constructing quantitative models from qualitative mutant phenotypes: preferences in selecting sensory organ precursors.

Bioinformatics (Oxford, England) - 1 Jun 2006

Hsu Chao-Ping, Lee Pei-Hsuan, Chang Ching-Wei, Lee Cheng-Tsung

Abstract excerpt

MOTIVATION: To study biology from the systems level, mathematical models that describe the time-evolution of the system offer useful insights. Quantitative information is required for constructing such models, but such information is rarely provided. RESULTS: We propose a scheme-based on random searches over a parameter space, according to criteria set by qualitative experimental observations-for inferring...

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PMID: 16522667
DOI: 10.1093/bioinformatics/btl082

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