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Article

Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram.

BMC systems biology - 1 Apr 2010

Li Chen, Nagasaki Masao, Saito Ayumu, Miyano Satoru

Abstract excerpt

BACKGROUND: With an accumulation of in silico data obtained by simulating large-scale biological networks, a new interest of research is emerging for elucidating how living organism functions over time in cells. Investigating the dynamic features of current computational models promises a deeper understanding of complex cellular processes. This leads us to develop a method that utilizes structural properties of...

Topics

Algorithms
Animals
Cell Physiological Phenomena
Circadian Rhythm
Computer Simulation
Drosophila
Models, Biological
Models, Theoretical
Mutation
Signal Transduction
Systems Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20356411
DOI: 10.1186/1752-0509-4-39
PMCID: PMC2855528

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