Article
Interlinked nonlinear subnetworks underlie the formation of robust cellular patterns in Arabidopsis epidermis: a dynamic spatial model.
BMC systems biology - 17 Nov 2008
Benítez Mariana, Espinosa-Soto Carlos, Padilla-Longoria Pablo, Alvarez-Buylla Elena R
Abstract excerpt
BACKGROUND: Dynamical models are instrumental for exploring the way information required to generate robust developmental patterns arises from complex interactions among genetic and non-genetic factors. We address this fundamental issue of developmental biology studying the leaf and root epidermis of Arabidopsis. We propose an experimentally-grounded model of gene regulatory networks (GRNs) that are coupled by...
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