Article
Rapid and label-free microfluidic neutrophil purification and phenotyping in diabetes mellitus.
Scientific reports - 6 Jul 2016
Hou Han Wei, Petchakup Chayakorn, Tay Hui Min, Tam Zhi Yang, Dalan Rinkoo, Chew Daniel Ek Kwang, Li King Ho Holden, Boehm Bernhard O
Abstract excerpt
Advanced management of dysmetabolic syndromes such as diabetes will benefit from a timely mechanistic insight enabling personalized medicine approaches. Herein, we present a rapid microfluidic neutrophil sorting and functional phenotyping strategy for type 2 diabetes mellitus (T2DM) patients using small blood volumes (fingerprick ~100 μL). The developed inertial microfluidics technology enables single-step...
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