Article
The functional polymorphism of erythropoietin gene rs1617640 G>T is not associated with susceptibility and clinical outcome of early-stage breast cancer.
Anticancer research - 1 Aug 2012
Szkandera Joanna, Absenger Gudrun, Stotz Michael, Weissmueller Melanie, Winder Thomas, Langsenlehner Tanja, Samonigg Hellmut, Renner Wilfried, Schippinger Walter, Gerger Armin
Abstract excerpt
Recent data suggest that erythropoietin (EPO) plays a substantial role in cancer development and clinical outcome by stimulating cell proliferation, invasion and angiogenesis. A functional polymorphism (rs1617640 G>T) in the promoter region of the EPO gene increases EPO protein expression. In the present study, we investigated the association of EPO rs1617640 G>T with susceptibility and clinical outcome of...
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